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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLD3 All Species: 22.73
Human Site: S263 Identified Species: 50
UniProt: Q8IV08 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IV08 NP_001026866.1 490 54705 S263 Q A G S S I P S T W P R F Y D
Chimpanzee Pan troglodytes XP_524268 446 49752 V227 D W R S L T Q V K E L G V V M
Rhesus Macaque Macaca mulatta XP_001094274 490 54730 S263 Q A G S S I P S T W P R F Y D
Dog Lupus familis XP_853110 490 54674 S263 Q A G S S I P S T W P R P Y D
Cat Felis silvestris
Mouse Mus musculus O35405 488 54371 S261 Q A G S S I P S T W P R S F D
Rat Rattus norvegicus Q5FVH2 488 54381 S261 Q A G S S I P S T W P R P F D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421399 517 59127 S270 H A S A T I P S P W P Q N Y S
Frog Xenopus laevis Q6PB03 493 56202 S264 L P N A T L P S P W P A N Y S
Zebra Danio Brachydanio rerio XP_001340066 482 54690 H258 Q T K T V P A H W P N K Y S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610093 494 55569 P275 N S E S S R I P D W D W R Y A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17405 516 58554 I252 S D I A T L Y I G S A N M D W
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.8 98.5 97.3 N.A. 93.2 93.8 N.A. N.A. 40.8 53.5 50.6 N.A. 41.2 N.A. 36.8 N.A.
Protein Similarity: 100 91 98.9 98.9 N.A. 97.1 96.9 N.A. N.A. 58.4 69.9 68.1 N.A. 56.8 N.A. 55.2 N.A.
P-Site Identity: 100 6.6 100 93.3 N.A. 86.6 86.6 N.A. N.A. 46.6 33.3 6.6 N.A. 26.6 N.A. 0 N.A.
P-Site Similarity: 100 6.6 100 93.3 N.A. 93.3 93.3 N.A. N.A. 66.6 53.3 26.6 N.A. 33.3 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 55 0 28 0 0 10 0 0 0 10 10 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 0 0 0 0 0 0 10 0 10 0 0 10 46 % D
% Glu: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 19 19 0 % F
% Gly: 0 0 46 0 0 0 0 0 10 0 0 10 0 0 0 % G
% His: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 55 10 10 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 0 0 10 0 0 10 0 0 0 % K
% Leu: 10 0 0 0 10 19 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % M
% Asn: 10 0 10 0 0 0 0 0 0 0 10 10 19 0 0 % N
% Pro: 0 10 0 0 0 10 64 10 19 10 64 0 19 0 0 % P
% Gln: 55 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 10 0 0 10 0 0 0 0 0 46 10 0 0 % R
% Ser: 10 10 10 64 55 0 0 64 0 10 0 0 10 10 19 % S
% Thr: 0 10 0 10 28 10 0 0 46 0 0 0 0 0 10 % T
% Val: 0 0 0 0 10 0 0 10 0 0 0 0 10 10 0 % V
% Trp: 0 10 0 0 0 0 0 0 10 73 0 10 0 0 10 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 10 55 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _